Diabetes, genetics and what would happen to our children

[Anita]

[quote:ec9843fc21]I know people who are eating properly, never in excess, thin and fit and who have diabetes. Genes are the culprits in thoses cases.[/quote:ec9843fc21]
I have to agree with Gemstone - genes play a major rule in this.
Yes - some people might become diabetic due to pumping sugar (I know someone that got it by drinking carrot juice several times a day - would you belive this??) but they were probably prone to the problem from the start... This happens in many other deseases, including cancer.

[csr18]

Before i was diagnosed i was hooked on rice pudding and was eating probably too much of it. Then i started having the usual symtoms and eventually lost about 3 stone in weight. When my local GP checked my sugar it was above 20mmol.
So that might have been the catalyst for my developing the condition that was in my genes.

[Anita]

[quote:025ac73e06]So that might have been the catalyst for my developing the condition that was in my genes.[/quote:025ac73e06]
Sounds like this is the case.
I told you already I know of a guy that drank [b:025ac73e06]a lot[/b:025ac73e06] of carrot juice and as a result became a T2. The doctors said that this was the catalyst.
This is why we [b:025ac73e06]MUST[/b:025ac73e06] keep an eye on our children, as they are prone to get this disease and they might prevent it if they keep the right life style.

As for T1s, I think it's almost 100% genetic, but I'm not sure on that.

[Gemstone]

[quote="Anita"]

This is why we MUST keep an eye on our children, as they are prone to get this disease and they might prevent it if they keep the right life style.

My Dr. said that my kids have 90% chances to have diabetes because my hubby and me have it and it runs in both families.

[Anita]

Can't you do something about it???
I mean if starting at childhood, they will have the proper lifestyle they still have 90% to get it?

[csr18]

I think i heard/read somewhere that it skips a generation.
I'm looking into that now, will post here if/when i find out.
Neither of my parents are diabetic but my dads grandparent was.

"[u:0b76970100]Herititary Tendencies in Type 1 Diabetes[/u:0b76970100]
Type 1 Diabetes tends to have less tendency to have other family members affected with diabetes than Type 2. In the first large family study of diabetes, less than 4% of parents and 6% of siblings of a person with diabetes also had diabetes. In studies with identical twins less than 50% of the siblings of a person with diabetes also had diabetes versus almost 100% of siblings of people with Type 2 Diabetes. Children of Type 1 diabetic fathers are more likely to develop Type 1 autoimmune diabetes than children of Type 1 diabetic mothers."
From Endocrine Web's Diabetes Center

[Gemstone]

Yes, I agree for type 1. Though I know a brother and sister who both have type 1 while others in the extended family have type 2. There is exceptions for each rules.

As for type 2... son, husband and father in law, that's 3 generations in a row who have it.

You know, with the extend of this illness now, taking epidemic proportion in North America, I think the researchers will make new discoveries and most bases will be changed. I know so many people with diabetes that it's scary.

What is even scariest, it's that I don't know a single person who take his blood glucose test more than once a day!!!

[csr18]

I do believe that the genetic predisposition can be exacerbated by overeating etc.
Is it not a fact that the condition can present in someone when they are pregnant or have an operation or other type of trauma?
So the 'pumping' of sugar or unhealthy lifestyle (maybe) could speed up the process as the person is putting quite a load on their system?
I agree with Gemstone, because of the amount of new cases there is going to be more research into the why,when and how we get it.

By the way, i test myself up to 20 times a day and always have done, but i'm like that.

[Gemstone]

I do believe that the genetic predisposition can be exacerbated by overeating etc.
Is it not a fact that the condition can present in someone when they are pregnant or have an operation or other type of trauma?
So the 'pumping' of sugar or unhealthy lifestyle (maybe) could speed up the process as the person is putting quite a load on their system?
I agree with Gemstone, because of the amount of new cases there is going to be more research into the why,when and how we get it.

By the way, i test myself up to 20 times a day and always have done, but i'm like that.

Yes, genetic predisposition can be exacerbated by overeating and lack of exercice, for type 2 only. Gestationnal diabetes is completely something else though someone having it have bigger chances to get diabetes later in life. A surgery or trauma is a shock and could trigger it.

As you are on insulin, there is a bigger need to test. I test an average of 7 times a day, sometimes more because of hypoglycemic episodes often at the end of the afternoon and late evening. I found that if I get too loose on my testing, I also get loose on my diet and it's not good at all.

[Anita]

[quote:0cfaf0d045="peter c"]As for the carrot jiuice thingy - that is sheer bunkum.[/quote:0cfaf0d045]
Go tell him it's a 'sheer bunkum'... good luck!

The situation was probably that he was genetically prone to get diabetic and the fact that he ate a lot of sugar (or drank it in this case) caused the disease to emerge.
As you know this is the case with many genetic diseases, take for example skin cancer - the 'whiter' you are, the higher the probability you'll get it, still it needs some other 'outside' effects like being in the sun...
So overall, it's a combination of genes and external parameters.